Compared with A164H, your hypercontractility observed along with constitutive protonation from residue 164 (cTnI A164R) with baseline sustains this kind of summary. Thus, with physical pH, WT cTnI as well as cTnI A164H have got comparable molecular inotropic capabilities mediated by constitutionnel characteristics generally involving?intermolecular hydrophobic side-chain contacts along with cTnC (


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