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Accordingly, we developed a murine model of severe ischemia to allow methodical testing of relevant clinical parameters. High femoral artery ligation and total excision of the superficial femoral artery was performed on C57BL/6 mice. MNC were isolated from the bone marrow of donor mice and injected into the semimembranosus or gastrocnemius #links# muscle. Vascular and functional outcomes were meas

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